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BrainVTA

Construction and Packaging Service of virus Vector

Construction and Packaging Services of AAV

Large scale AAV production

Adeno-Associated Virus (AAV)
 BrainVTA offers research grade, high quality AAV vectors with titers from 1 x1012 to 1 x1013 vg/ml. AAV vectors are prepared by eithe baculovirus infection in SF-9 insect cells or by a triple plasmid transfection in HEK-293 cells. Purified vector preparations are subjected to a variety of quality control measures including QPCR titer to asses viral genomes and silver stain to further assess titer and viral purity. Control stocks are assayed for Cre recombinase and Luciferase activity.
 
How do I obtain virus packaging services?
 
● You can directly obtain Products from the spot list. Click here for more In Stock AAV Vectors Service.
● Also, You can obtain customized service using our highly intuitive free online vector design tool. To use the tool, click the Design My Vector button. Once you finish designing a vector, you will have the option to put the customized service in your shopping cart.
 
● Lastly, If you are unable to use our online tool to design your desired vector or if you have other service needs, just submit your needs to us by clicking the Send Request button. Our scientists will send you a link to a service proposal including price, turnaround and other relevant information. You can add the proposal to your shopping cart.
 
Virus serotypes
 
BrainVTA currently offers the following serotypes: 1, 2, 5, 6, 8, 9, rh10, DJ, DJ8,PHP.B, PHP.eB, PHP.S,retro,anc80. Novel peptide modified serotypes can also be produced on a case-by-case basis. Tissue specificity is determined by the serotype. If you Don't know which AAV serotype to use, See Table 1 to explore available AAV serotype to meet the efficient delivery of gene into the cells or tissues of interest. 
Table 1  Target specificity of different AAV serotypes
  Serotype    Tropism
  AAV1    Muscle, Heart, CNS, Eye, Lung
  AAV2    In vitro, CNS
  AAV3    Human Liver Cancer Cells
  AAV4    CNS, RPE
  AAV5    Lung (airway, alveoli), Eye, CNS
  AAV6    Muscle, Lung, Heart, Adipose, Liver
  AAV8    Liver, Muscle, Eye, CNS, Adipose
  AAV9    Lung (alveoli), Liver, Muscle, Heart, CNS, Adipose
  AAVDJ    In vitro, Liver, Heart, Kidney
  AAVrh10    Pleura, CNS
 
Tissue-specific promoters
 
BrainVTA also offers Various Tissue-specific promoters. Listed below are the most commonly chosen promoters. Don't see the promoter of interest, Please inquire.

50% discount for Pre-Made AAVs